Johnny Depp's legal battles led to his departure from the 'Fantastic Beasts' franchise after a libel suit against The Sun

Anne Hathaway missed out on a role in 'Knocked Up' due to discomfort with a realistic delivery scene

Lisa Kudrow's journey to 'Friends' began with being let go from the sitcom 'Frasier' before landing her iconic role

Holly Hunter's voiced character in 'Chicken Little' was changed from female to male, replacing her work with Zach Braff

Henry Cavill's future as Superman became uncertain under the new direction of director James Gunn in the DC Universe

Esteemed actor Frank Langella was fired from the Netflix series 'The Fall of the House of Usher' due to misconduct allegations

Ezra Miller's erratic behavior and multiple troubling incidents put their role in 'The Flash' movie in question